Author | Mickael Gay and Lucy T. Zhang |
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Title | Numerical studies of blood flow in healthy, stenosed, and stented carotid arteries |
Year | 2008 |
Journal | International Journal for Numerical Methods in Fluids |
Publisher | Wiley InterScience |
Abstract | Numerical analysis of pulsatile blood flow in healthy, stenosed, and stented carotid arteries is performed with the aim of identifying hemodynamic factors in the initiation, growth, and the potential of leading to severe occlusions of a diseased artery. The Immersed Finite Element Method is adopted for this study to conveniently incorporate various geometrical shapes of arteries without remeshing. Our computational results provide detailed quantitative analysis on the blood flow pattern, wall shear stress, particle residence time, and oscillatory shear index. The analysis of these parameters leads to a better understanding of blood clot formation and its ocalization in a stenosed and a stented carotid artery. A healthy artery is also studied to establish a baseline comparison. This analysis will assist in developing treatments for diseased arteries and novel stent designs to reduce restenosis. KEY WORDS: carotid artery; stenosis; stent; wall shear stress; oscillatory shear index; residence time; Immersed Finite Element Method |
PDF File | Download |
DOI Link | 10.1002/fld.1966 |